Purified anti-human CD90 (Thy1)

Antibodies Single
Sony
5E10
Other
Mouse IgG1, κ
Human
HEL cells
2240505
$85.00

Description

CD90 is a 25-35 kD GPI-anchored protein, also known as Thy-1. It belongs to the Ig superfamily. Human CD90 is expressed on neuronal cells, a subset of CD34+ cells, a subset of fetal liver cells and fetal thymocytes, fibroblasts, activated endothelial cells, and some leukemia cell lines. CD34+CD90+ cells are primitive hematopoietic stem cells. It has been reported that Thy-1 binds with β2 and β3 integrins and plays bimodal roles in the regulation of cell adhesion and neurite outgrowth, and inhibits hematopoietic stem cells proliferation and differentiation.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 microg per million cells in 100 microL volume. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Craig W, et al. 1993. J. Exp. Med. 177:1331. (IP)
2. Gundlach CW 4th, et al. 2011. Bioconjug. Chem. 22:1706. (Pig Reactivity)
3. Touboul C, et al. 2013. J. Transl. Med. 11:28. (IF)
4. Bradley JE, et al. 2013. Lab Invest. 93:365. (Epitope)
5. Donnenberg VS, et al. 2010. Cytometry B. Clin. Cytom. 5:287. (IHC)