Purified anti-human CD42b

Antibodies Single
Sony
HIP1
Other
Mouse IgG1, κ
Human
100 µg
2119510
$104.00

Description

CD42b is a 145 kD glycoprotein known as gpIbα. It is covalently bonded to CD42c to form GPIb. CD42b is expressed on platelets and megakaryocytes. CD42b/c heterodimer forms a complex with CD42a and d and acts as the receptor for von Willibrand factor and thrombin.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 microg per 106 cells in 100 microL volume or 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Knapp W, et al. 1989. Leucocyte Typing IV. Oxford University Press. New York.
2. Takahashi R, et al. 1999. Blood. 93:1951.
3. Saggu G, et al. 2013. J. Immunol. 190:6457. PubMed
4. Meyer Dos Santos S, et al. 2011. Blood. 117:4999. (Block) PubMed
5. Vettore S, et al. 2008. Haematologica. 93:1743.