Purified anti-human CD33

Antibodies Single
Sony
WM53
Other
Mouse IgG1, κ
Human
Human myeloid leukaemia cells.
100 µg
2117010
$104.00

Description

CD33 is a 67 kD type I transmembrane glycoprotein also known as Siglec-3, gp67, and p67. It is a sialoadhesion immunoglobulin superfamily member expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. CD33 is absent on normal platelets, lymphocytes, erythrocytes and hematopoietic stem cells. CD33 functions as a sialic acid-dependent cell adhesion molecule with carbohydrate/lectin binding activity.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 microg per million cells in 100 microL volume. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Knapp W, et al. 1989. Leucocyte Typing IV. Oxford University Press. New York.
2. Favaloro E, et al. 1988. Br. J. Haematol. 69:163.
3. Garnache-Ottou F, et al. 2005. Blood 105:1256. (WB)
4. Pèrez-Oliva AB, et al. 2011. Glycobiology. 21:757. (epitope, FC, IF)