Purified anti-human CD210 (IL-10 R)

Antibodies Single
Sony
3F9
Other
Rat IgG2a, κ
Human
shIL-10R
100 µg
2144010
$116.00

Description

CD210, also known as the IL-10 receptor, is a 90-110 kD protein expressed on T cells, B cells, NK cells, monocytes and macrophages. CD210 belongs to the class II cytokine receptor family which includes the IFN-γ receptor (CDw119), the IFN-α/β receptor (CD118) and tissue factor (CD142). The IL-10 receptor is involved in signal transduction by inducing phosphorylation of STAT1a and STAT3 and by inducing activation of Jak1 and Tyk.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 microg per million cells in 100 microL volume. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Liu Y, et al. 1997. J. Immunol. 158:604. (Immunogen, IP, Block)
2. Levings MK, et al. 2005. Blood 105:1162. (Block)
3. Goodier MR, et al. 2000. J. Immunol. 165:139. (Block)
4. Huang YH, et al. 2009. J. Leukoc. Biol. 86:273. PubMed
5. Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
6. Liu BS,et al. 2011. J Leukoc Biol. 89:981. PubMed
7. Joffe M, et al. 2012. Int Immunol. 24:447. PubMed
8. MacDonald KP, et al. 1999. J. Immunol. 163:5599. (epitope)