PerCP/Cy5.5 anti-human CD134 (OX40)

Antibodies Single
Sony
Ber-ACT35 (ACT35)
Flow Cytometry
Mouse IgG1, κ
Human
HTLV 1-transformed HUT 102 cells
2350045

Description

CD134, also known as OX40 and TNFRSF4, is a 50 kD type I transmembrane glycoprotein. It is a member of the TNF receptor family. OX40 is expressed on activated T lymphocytes including Th1, Th2, Th17, and Treg cells. The interaction of OX40 with OX40L results in B cell proliferation and antibody secretion, regulation of primary T cell expansion, and T cell survival. OX40 influences the size of the T cell memory pool and regulation of CD4+ T cell tolerance.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 microL per million cells or 5 microL per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

* PerCP/Cy5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

References

1. Latza U, et al. 1994. Eur. J. Immunol. 24:677. (WB, IP)
2. Durkop H, et al. 1995. Brit. J. Haematol. 91:927. (IHC)
3. Durkop H, et al. 1997. Brit. J. Haematol. 98:863. (IHC)
4. Willett B, et al. 2007. J. Virol. 81:9665. (ELISA)
5. Li M and Zhang Y. et al. 2005. Cell. Mol. Immunol. 2:467. (FA)
6. Gloviczki ML, et al. 2012. Clin. J. Am. Soc. Nephrol. 8:546. PubMed
7. Domingos PL, et al. 2012. An. Bras. Dermatol. 87:851. (IHC)