PE/Cy7 anti-human CD134 (OX40)

Antibodies Single
Sony
Ber-ACT35 (ACT35)
Flow Cytometry
Mouse IgG1, κ
Human
HTLV 1-transformed HUT 102 cells
100 tests
2350060
$306.00

Description

CD134, also known as OX40 and TNFRSF4, is a 50 kD type I transmembrane glycoprotein. It is a member of the TNF receptor family. OX40 is expressed on activated T lymphocytes including Th1, Th2, Th17, and Treg cells. The interaction of OX40 with OX40L results in B cell proliferation and antibody secretion, regulation of primary T cell expansion, and T cell survival. OX40 influences the size of the T cell memory pool and regulation of CD4+ T cell tolerance.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microL to 5 microL per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microL staining volume or per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Latza U, et al. 1994. Eur. J. Immunol. 24:677. (WB, IP)
2. Durkop H, et al. 1995. Brit. J. Haematol. 91:927. (IHC)
3. Durkop H, et al. 1997. Brit. J. Haematol. 98:863. (IHC)
4. Willett B, et al. 2007. J. Virol. 81:9665. (ELISA)
5. Li M and Zhang Y. et al. 2005. Cell. Mol. Immunol. 2:467. (FA)
6. Gloviczki ML, et al. 2012. Clin. J. Am. Soc. Nephrol. 8:546. PubMed
7. Domingos PL, et al. 2012. An. Bras. Dermatol. 87:851. (IHC)