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- Sony Biotechnology
- Sony Biotechnology
CD150 is a 70-95 kD type I transmembrane glycoprotein also known as SLAM or IPO-3. It is a member of the Ig superfamily. It is expressed on a subset of T cells, B cells, dendritic cells, and endothelial cells. The expression of CD150 is upregulated upon activation. CD150 binds to itself as the ligand to be involved in B cell costimulation, proliferation, immunoglobulin production, and signal transduction.
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microL to 5 microL per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microL staining volume or per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
1. Garcia V, et al. 2001. J. Immunol. 167:5719. (Costim)
2. Vincent S, et al. 2002. J. Virol. 76:6121.
3. Cocks B, et al. 1995. Nature 376:260.
4. Sayos J, et al. 2001. Blood 97:3867. (IP)
5. Aversa G, et al. 1997. J. Immunol. 158:4036. (Costim)
6. Spencer M, et al. 2010. Am. J. Physiol Endocrinol Metab. 299:1016. PubMed
7. Grass GD, et al. 2013. J Biol Chem. 288:26089. PubMed