Biotin anti-human CD38

Antibodies Single
Sony
HIT2
Flow Cytometry,Immunohistochemistry
Mouse IgG1, κ
Human
100 µg
2117590
$93.00

Description

CD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscles, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 microg per million cells in 100 microL volume. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Kishimoto T, et al. Eds. 1997. Leucocyte Typing VI. Garland Publishing Inc. London.
2. Dieu M. 1998. J. Exp. Med. 188:373.
3. Esser M, et al. 2001. J. Virol. 75:6173.
4. Jeannin P, et al. 1999. J. Immunol. 162:2044.
5. Kapsogeorgou EK, et al. 2001. J. Immunol. 166:3107.
6. van der Voort R, et al. 1997. J. Exp. Med. 185:2121. (IHC)
7. Bende RJ, et al. 2003. Am. J. Pathol. 162:105.
8. Lehner M, et al. 2008. J. Leukoc. Biol. 83:883. PubMed
9. Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)