APC anti-human CD2

Antibodies Single
Sony
RPA-2.10
Flow Cytometry
Mouse IgG1, κ
Human
2101070
$272.00

Description

CD2 is a 50 kD type I transmembrane glycoprotein also known as LFA-2, T11, and sheep red blood cell receptor (SRBC-R). This immunoglobulin superfamily member is expressed on thymocytes, T lymphocytes, NK cells, and thymic B cell subsets. The major ligand for CD2 is CD58 (also known as LFA-3). CD2 has also been reported to bind CD48, CD59, and CD15. CD2 plays a critical role in alternative T cell activation, T cell signaling, and cell-cell adhesion.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microL to 5 microL per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microL staining volume or per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Knapp W, et al. Eds. 1989. Leucocyte Typing IV. Oxford University Press. New York.
2. Aversa G, et al. 1987. Transplant. Proc. 19:277. (Block)
3. Zaretsky AG, et al. 2009. J. Exp Med. 206:991. (IHC) PubMed
4. Perona-Wright G, et al. 2010. Nat. Immunol. 11:520. (FC) PubMed
5. Thummler K, et al. 2010. J. Leukoc. Biol. 88:1041. 
6. Kap Y, et al. 2009. J. Histochem. Cytochem. 57:1159. (IHC)
7. Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)