APC anti-human CD13

Antibodies Single
Sony
WM15
Flow Cytometry
Mouse IgG1, κ
Human
2108525

Description

CD13 is a 150-170 kD type II transmembrane glycoprotein also known as aminopeptidase N, APN, and gp150. This zinc metallopeptidase is expressed as a homodimer on granulocytes, myeloid progenitors, endothelial cells, epithelial cells and subset of granular lymphoid cells. It is not expressed on platelets or erythrocytes. CD13 is thought to be involved in the metabolism of many regulatory peptides and functions in antigen processing and the cleavage of chemokines such as MIP-1. CD13 serves as the cellular receptor for Coronavirus.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microL to 5 microL per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microL staining volume or per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Knapp W, et al. 1989. Leucocyte Typing IV. Oxford University Press. New York.
2. Saiki I, et al. 1993. Int J Cancer. 54:137. (Block)
3. Rosenzwajg M, et al. 2000. Blood 95:453. (Block)
4. Kawase M, et al. 2008. J Virol. 83:712. (Block) PubMed
5. Di Matteo P, et al. 2011. J. Histochem. Cytochem. 59:47. (IHC)