Alexa Fluor® 647 anti-human HLA-DR

Antibodies Single
Sony
LN3
Flow Cytometry
Mouse IgG2b, κ
Human
human PBL
100 tests
2235060
$260.00

Description

The LN3 monoclonal antibody reacts with the HLA-DR antigen, a member of MHC class II molecules. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 microL per million cells or 5 microL per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633nm / 635nm.

References

1. Marder RJ, et al. 1985. Lab. Invest. 52:497.
2. Norton AJ and Isaacson PG. 1987. Am. J. Pathol. 128:225.
3. Hua ZX, et al. 1998. Hum. Pathol. 29(12):1441.