Alexa Fluor® 488 anti-human CD83

Antibodies Single
Sony
HB15e
Flow Cytometry
Mouse IgG1, κ
Human
100 tests
2126570
$290.00

Description

CD83 is a 43 kD single chain type I glycoprotein also known as HB15. A member of the immunoglobulin superfamily, CD83 is expressed on a subset of dendritic cells, Langerhans cells, and weakly on activated lymphocytes. Although CD83 is thought to play a role in antigen presentation and/or lymphocyte activation, the precise function of this protein is unknown. CD83 is considered to be a useful marker for mature dendritic cells.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 microL per million cells or 5 microL per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.

References

1. Knapp W, et al. 1989. Leucocyte Typing IV. Oxford University Press New York.
2. Zhou L, et al. 1995. J. Immunol. 154:3821.
3. Cao W, et al. 2005. Biochem. J. 385:85.
4. Lore K, et al. 2002. AIDS 16:683. (IHC)
5. Cho H, et al. 2007. Physiol Genomics doi:10.1152/physiolgenomics.00051.2006
6. Banik S, et al. 2013. Infect Immun. 81:2309. PubMed