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- Sony Biotechnology
- Sony Biotechnology
CD92, also known as CDW92 and CTL1, is a 70kD choline transporter-like transmembrane protein. CD92 is important for transport of choline across the membrane for synthesis of cell membrane components and the neurotransmitter, acetylcholine. CD92 is primarily expressed on monocytes and neutrophils, but can also be found on other myeloid and T-cell subsets. Ionomycin or calcium ionophore mediates the maturation of monocytic dendritic cells causing down-regulation of CD92 but treatment with IL-10 causes re-expression.
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.5 microg per million cells in 100 microL volume. It is recommended that the reagent be titrated for optimal performance for each application.
1. Wille S, et al. 2001. J. Immunol. 167:5795.