PE/Cy7 anti-human IFN-γ

Antibodies Single
Sony
B27
Flow Cytometry
Mouse IgG1, κ
Human
<I>E. coli</I>-expressed recombinant human IFN-γ
3132590
$318.00

Description

Interferon-γ is a potent multifunctional cytokine which is secreted primarily by activated NK cells and T cells. Originally characterized based on anti-viral activities, IFN-γ also exerts anti-proliferative, immunoregulatory, and proinflammatory activities. IFN-γ can upregulate MHC class I and II antigen expression by antigen-presenting cells. The B27 antibody reacts with the human interferon-γ. The B27 antibody can neutralize the bioactivity of natural or recombinant IFN-γ.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microL to 5 microL per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microL staining volume or per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Favre C, et al. 1989. Molec. Immunol. 26:17. (Neut)
2. Kaur A, et al. 2002. J Virol. 76:3646.
3. Abrams J, et al. 1992. Immunol. Rev. 127:5. (Neut)
4. Andersson U, et al. 1999. Detection and quantification of gene expression. New York:Springer-Verlag.
5. Rout N, et al. 2010. PLoS One 5:e9787. (FC)
6. Acosta-Rodriguez EV, et al. 2007. Nat. Immunol. 9:942-9. (Neut)
7. Gangur V, et al. 1998. FASEB J. 12:705-13. (Neut)