Description

FOXA1 is a transcriptional activator that is required for tissue-specific differentiation during embryonic development. It also functions as a coactivator with nuclear hormone receptors, including ESR1, and has been shown to play a major role in driving estrogen receptor positive breast cancers.

Recommended Usage

Each lot of this antibody is quality control tested. For flow cytometric staining, the suggested use of this reagent is ≤0.65 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Besenard V, et al. 2004. Gene Expr Patterns. 5:193-208. (IHC-P)