Purified anti-Tubulin β 3 (TUBB3)
Description
Tubulin is the main component of microtubules. In adults, tubulin beta 3 (TUBB3) is primarily expressed in neurons and is commonly used as a neuronal marker. It plays an important role in neuronal cell proliferation and differentiation. Mutations in this gene cause congenital fibrosis of the type 3 extraocular muscles. Tubulin beta 3 (TUBB3) is also found in a wide range of tumors. Studies indicate that it is a predictive and prognostic marker in various tumors.
Formulation
Phosphate-buffered solution + 0.03% Thimerosal.Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 1.0 – 5.0 µg/ml is suggested. For Western blotting, the suggested use of this reagent is 1.0 – 5.0 µg/ml. For immunocytochemistry, a concentration range of 1.0 – 5.0 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.