PE anti-mouse Perforin

Antibodies Single
Sony
S16009A
Intracellular Flow Cytometry
Rat IgG2a, κ
Mouse
Mouse perforin transfected cells.
1371530
$352.00

Description

Perforin is a 70 kD cytolytic protein that is expressed in the cytoplasmic granules of cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells. Perforin is one of the major effector molecules used by cytotoxic T cells and NK cells to mediate targeted cell lysis.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Podack ER, et al. 1988. Immunol. Rev. 103:203.
2. Konjar S, et al. 2010. Immunology. 131:257.
3. Trapani JA, et al. 2002. Nat. Rev. Immunol. 2:735.
4.