PE anti-human IL-9

Antibodies Single
Sony
MH9A4
Flow Cytometry
Mouse IgG2b, κ
Human
Baculovirus-expressed, recombinant human IL-9
3138015
$174.00

Description

IL-9 is a potent, T cell-derived, T cell growth factor which can also enhance mast cell activity and IL-3- or IL-4- dependent proliferation of bone marrow-derived mast cells. IL-9 synergizes with erythropoietin to promote erythroid colony formation. IL-9 has also been reported to protect human T cells from apoptosis induced by IL-2 withdrawal. IL-9 is upregulated in human eosinophils by TNF-α and IL1-β. IL-9 has been reported to downregulate the oxidative burst in activated human alveolar macrophages and induce TGF-β production. The recently characterized Th-9 helper cell lineage is characterized by the production of IL-9. The MH9A4 antibody reacts with human IL-9. The MH9A4 antibody can neutralize the bioactivity of natural or recombinant IL-9.

Formulation

test sizes: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
microg size: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microL to 5 microL per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microL staining volume or per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Jenmalm M, et al. 2001. Clin. Exptl. Aller. 31:1528.
2. Faulkner H, et al. 2002. J. Infec. Diseas. 185:665.
3. Chang HC, et al. 2010. Nat. Immunol. 11:527. (ELISA) PubMed