PE anti-human Delta-like protein 1 (DLL1)

Antibodies Single
Sony
MHD1-314
Flow Cytometry
Mouse IgG1, κ
Human
hu DLL1-hu IgG Fc fusion protein
2332020
$324.00

Description

Delta-like protein 1 is a type I transmembrane protein. The mature form consist of an extracellular domain of 528 amino acids (aa) that contain a DSL domain and eight tandem EGF repeats; the transmembrane region is 23 aa long and has a 155 aa cytoplasmic domain. After the binding of Notch receptors, the extracellular and cytoplasmic domains are cleaved, and the later is translocated into the cell nucleus to regulate gene expression. Delta-like protein 1 is expressed in heart and pancreas and in a lower amount in brain and muscle. During fetal life, it is transiently expressed during gastrulation and early organogenesis and its expression remains through adult life in hematopoietic tissues and the cortico-medullary region of the thymus.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microL to 5 microL per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microL staining volume or per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Kim H, et al. 2015. Cytotherapy. 17:579. PubMed