PE anti-human CD325 (N-Cadherin)

Antibodies Single
Sony
8C11
Flow Cytometry
Mouse IgG1, κ
Human
Recombinant human N-cadherin extracellular domain
2354025
$272.00

Description

CD325 (N-cadherin) is a 130 kD, single pass transmembrane protein. Its extracellular region consists of five EC domains and has one cytoplasmic domain. N-cadherin is involved in organogenesis and maintenance of organ architecture by contributing to the sorting of heterogeneous cell types and in the cell adhesion needed to form tissues. N-cadherin is expressed by stem cells, myeloblasts, endothelial cells, and fibroblasts, and also is expressed in neural and muscle tissues and some types of carcinoma cells. CD325 associates with the cytoskeleton trough catenin proteins.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microL to 5 microL per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microL staining volume or per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Navarro P, et al. 1998. J. Cell Biol. 140:1475. (IF)
2. Kim JB. 2000. J. Cell Biol. 151:1193. (Block, WB)
3. Puch S, et al. 2001. J. Cell. Sci. 114:1567. (IF)
4. Wahl JK. 3rd, et al. 2003. J. Biol. Chem. 278:17269. (WB)
5. Wein F, et al. 2010. Stem. Cell Res. 4:129. (FC)
6. Jaggi M, et al. 2002. Cell. Commun. Adhes. 9:103. (IF)
7. Cai X, et al. 2014. PLoS One. 9:108942. PubMed
8. Zhang W, et al. 2015. PLoS One. 10:125995. PubMed