SI8000 Cell Motion Brochure

Regenerative medicine

1. Endothelin-1 Induces Myofibrillar Disarray and Contractile Vector Variability in Hypertrophic Cardiomyopathy–Induced Pluripotent Stem Cell–Derived Cardiomyocytes
   A. Tanaka, S. Yuasa, G. Mearini; T. Egashira, T. Seki, M. Kodaira, D. Kusumoto, Y. Kuroda, S. Okata, T. Suzuki, T. Inohara, T. Arimura, S. Makino, K. Kimura, A. Kimura, T. Furukawa, L. Carrier, K. Node and K. Fukuda
   Journal of the American Heart Association 3:e001263 10.1161/JAHA.114.001263, 2014
   http://www.ncbi.nlm.nih.gov/pubmed/25389285
2. Pivotal Role of Non-cardiomyocytes in Electromechanical and Therapeutic Potential of Induced Pluripotent Stem Cell-Derived Engineered Cardiac Tissue
   Iseoka H., Miyagawa S., Fukushima S., Saito A., Masuda S., Yajima S., Ito E., Sougawa N., Takeda M., Harada A., Lee JK. and Sawa Y.
   Tissue Engineering: Part A. doi: 10.1089/ten.TEA.2016.0535, 2017
   https://www.ncbi.nlm.nih.gov/pubmed/28498040

Live Imaging

1. Image-based evaluation of contraction-relaxation kinetics of human-induced pluripotent stem cell-derived cardiomyocytes: Correlation and complementarity with extracellular electrophysiology
   T. Hayakawa, T. Kunihiro, T. Ando, S. Kobayashi, E. Matsui, H. Yada, Y. Kanda, J. Kurokawa and T. Furukawa
   Journal of Molecular and Cellular Cardiology 77:178-191 10.1016/j.yjmcc.2014.09.010, 2014
   http://www.ncbi.nlm.nih.gov/pubmed/25257913
2. Noninvasive evaluation of contractile behavior of cardiomyocyte monolayers based on motion vector analysis
   T. Hayakawa, T. Kunihiro, S. Dowaki, H. Uno, E. Matsui, M. Uchida, S. Kobayashi, A. Yasuda, T. Shimizu and T. Okano
   Tissue Engineering: Part C Methods 11:21-32 10.1089/ten.TEC.2011.0273, 2012
   http://www.ncbi.nlm.nih.gov/pubmed/21851323
3. Flow-Dependent Endothelial YAP Regulation Contributes to Vessel Maintenance
   Nakajima H., Yamamoto K., Agarwala S., Terai K., Fukui H., Fukuhara S., Ando K., Miyazaki T., Yokota Y., Schmelzer E., Belting HG., Affolter M., Lecaudey V. and Mochizuki N.
   Developmental Cell 40(6):523-536.e6. doi: 10.1016/j.devcel.2017.02.019, 2017
   https://www.ncbi.nlm.nih.gov/pubmed/28350986

Developmental Biology

1. Evolution of the fish heart by sub/neofunctionalization of an elastin gene
   Y. Moriyama, F. Ito, H. Takeda, T. Yano, M. Okabe, S. Kuraku, F. W. Keeley and K. Koshiba-Takeuchi
   Nature Communications 7:10397 10.1038/ncomms10397, 2016
   http://www.ncbi.nlm.nih.gov/pubmed/26783159

Toxicology

1. Comprehensive in vitro cardiac safety assessment using human stem cell technology: Overview of CSAHi HEART initiative
   K. Takasuna, K. Asakura, S. Araki, H. Ando, K. Kazusa, T. Kitaguchi, T. Kunimatsu, S. Suzuki and N. Miyamoto
   Journal of Pharmacological and Toxicological Methods 83:42–54 10.1016/j.vascn.2016.09.004, 2017
   https://www.ncbi.nlm.nih.gov/pubmed/?term=10.1016%2Fj.vascn.2016.09.004
2. Chronic drug-induced effects on contractile motion properties and cardiac biomarkers in human induced pluripotent stem cell derived cardiomyocytes
   I. Kopljar, A. De Bondt, P. Vinken, A. Teisman, B. Damiano, N. Goeminne, I. Van den Wyngaert, D. J. Gallacher and H. R. Lu
   British Journal of Pharmacology [Online published] 10.1111/bph.13713, 2017
   https://www.ncbi.nlm.nih.gov/pubmed/28094846
3. Modelling Torsade de Pointes arrhythmias in vitro in 3D human iPS cell-engineered heart tissue
   Kawatou M., Masumoto H., Fukushima H., Morinaga G., Sakata R., Ashihara T. and Yamashita JK.
   Nature Communications. 8(1):1078. doi: 10.1038/s41467-017-01125-y, 2017
   https://www.ncbi.nlm.nih.gov/pubmed/29057872