PE/Cy7 anti-mouse CD11a/CD18 (LFA-1)

Antibodies Single
Sony
H155-78
Flow Cytometry
Rat IgG1, κ
Mouse
T<sub>H</sub>-derived anti-I-Aκ CTL clone A1 5.1.17
1305060
$318.00

Description

Lymphocyte function-associated antigen 1 or LFA-1 is a heterodimer composed of two members of the integrin family, αL (CD11a) and β2 (CD18).  LFA-1 is expressed primarily on lymphocytes, monocytes/macrophages, and granulocytes.  It is involved in cell adhesion and costimulation processes. The ligands for LFA-1 are ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 microg per million cells in 100 microL volume. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Pont S, et al. 1986. J. Immunol. 136:3750. (FC)