PE anti-human CD177

Antibodies Single
Sony
MEM-166
Flow Cytometry
Mouse IgG1, κ
Human
Human granulocytes
2179025
$121.00

Description

CD177 is also known as neutrophil specific antigen 1, NB1, and polycythemia rubra vera 1. It is a member of the uPAR family and is a GPI-linked cell surface glycoprotein with a molecular weight of 60 kD. CD177 is expressed on granulocytes and bone marrow progenitors (early erythroblasts, megakaryocytes). It is thought to be involved in allogeneic and autoimmune responses to neutrophils.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 microL per million cells or 5 microL per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Leucocyte Typing VII. Mason D, et al. Eds, 2002 Oxford University Press.
2. von Vietinghoff S, et al. 2007. Blood 109:4487. PubMed
3. Korkmaz B, et al. 2008. J. Biol. Chem. 283:35976. PubMed
4. von Vietinghoff S, et al. 2007. Blood 109:4487. (IF)
5. Jankowska AM, et al. 2011. Haematologica. 96:954. (WB)