Purified anti-human CD5

Antibodies Single
Sony
UCHT2
Other
Mouse IgG1, κ
Human
100 µg
2103010
$104.00

Description

CD5 is a 67 kD single chain type I glycoprotein also known as Leu-1, Ly-1 and T1. It is a member of the scavenger receptor superfamily found on T cells, thymocytes, B cell subsets, chronic B lymphocytic leukemia (B-Cells), and peripheral blood dendritic cells. CD5 modulates T and B cell receptor signaling, thymocyte maturation, and T-B cell interactions upon binding to ligands such as CD72.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, it is recommended to use at ≤ 1.0 microg per 106 cells in 100 microL volume or 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Knapp W, et al. 1989. Leucocyte Typing IV Oxford University Press. New York.
2. Renaudineau Y, et al. 2005. Blood 106:2781. (WB IHC)
3. Porter JC and Hogg N. 1997. J. Cell Biol. 138:1437.
4. Saliba AE, et al. 2010. P. Natl. Acad. Sci. USA 107:14524. PubMed
5. Kap Y, et al. 2009. J. Histochem. Cytochem. 57:1159. (IHC)