PE anti-human CD18

Antibodies Single
Sony
TS1/18
Flow Cytometry
Mouse IgG1, κ
Human
2110535
$116.00

Description

CD18 is a 90-95 kD type I transmembrane protein also known as integrin β2 subunit, LFA-1 β subunit, and β2 integrin. CD18 non-covalently associates with CD11a, CD11b or CD11c. CD18 is expressed on all leukocytes. CD18 and associated α chains function in adhesion and signaling in hematopoietic cells.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microL to 5 microL per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microL staining volume or per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Schlossman S, et al. 1995. Leucocyte Typing V. Oxford University Press. New York.
2. Kishimoto T, et al. 1997. Leucocyte Typing VI. Garland Press. London.
3. Van Epps DE, et al. 1989. J. Immunol. 143:3207. (Block)
4. Meerschaert J, et al. 1994. J. Immunol. 152:1915. (Block)
5. Sithu SD, et al. 2007. J. Biol. Chem. doi:10.1074/jbc.M611273200.
6. Sommaggio R, et al. 2012. J. Immunol. 188:2075. PubMed
7. Hu D, et al. 2012. Eur J. Immunol. 42:69. PubMed
8. Valenzuela NM, et al. 2013. J. Immunol. 190:6635. PubMed