FITC anti-human CD38

Antibodies Single
Sony
HIT2
Flow Cytometry
Mouse IgG1, κ
Human
2117520
$93.00

Description

CD38 is a 45 kD type II transmembrane glycoprotein also known as T10. It is an ADP-ribosyl hydrolase expressed at variable levels on hematopoietic cells and in some non-hematopoietic tissues (such as brain, muscles, and kidney). In humans, it is expressed at high levels on plasma cells and activated T and B cells. By functioning as both a cyclase and a hydrolase, CD38 mediates lymphocyte activation, adhesion, and the metabolism of cADPR and NAADP. CD31 is the ligand of CD38.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microL to 5 microL per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microL staining volume or per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Kishimoto T, et al. Eds. 1997. Leucocyte Typing VI. Garland Publishing Inc. London.
2. Dieu M. 1998. J. Exp. Med. 188:373.
3. Esser M, et al. 2001. J. Virol. 75:6173.
4. Jeannin P, et al. 1999. J. Immunol. 162:2044.
5. Kapsogeorgou EK, et al. 2001. J. Immunol. 166:3107.
6. van der Voort R, et al. 1997. J. Exp. Med. 185:2121. (IHC)
7. Bende RJ, et al. 2003. Am. J. Pathol. 162:105.
8. Lehner M, et al. 2008. J. Leukoc. Biol. 83:883. PubMed
9. Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)