PerCP anti-human CD203c (E-NPP3)

Antibodies Single
Sony
NP4D6
Flow Cytometry
Mouse IgG1, κ
Human
HEK-293 cells transfected with human E-NPP3
2223075
$131.00

Description

CD203c, a transmembrane protein and a member of the ectoenzyme family, is involved in the hydrolysis of extracellular oligonucleotides, nucleoside phosphates, and NAD (possesses ATPase and ATP pyrophosphatase activity). The molecular weight of CD203c is between 130 and 150 kD under reducing conditions and 270 kD under non-reducing conditions. CD203c is expressed on basophils and mast cells, and is highly expressed on activated basophils. Secretory glands in endometrium and glioma cells are also positive. CD203c is a multifunctional ectoenzyme involved in the clearance of extracellular nucleotides whose substrates include nucleoside triphosphates, nucleoside diphosphates, cAMP, and NAD.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 microL per million cells or 5 microL per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

* PerCP has a maximum absorption of 482 nm and a maximum emission of 675 nm.

References

1. Bühring HJ, et al. 1999. Blood 94:2343.
2. Bühring HJ, et al. 2001. Blood 97:3303.
3. Platz IJ, et al. 2001. Int. Arch. Allergy Immunol. 126:335.
4. Charles N, et al. 2010. Nat. Med. 16:701. (FC) PubMed
5. Gernez Y, et al. 2011. Int. Arch. Allergy Immunol. 154:318. (FC) PubMed