Toggle Nav
    cart icon My Cart
  • shopping list
  • region-flag Sony Biotechnology
  • Home
  • Purified anti-human CD1a

Purified anti-human CD1a

Purified anti-human CD1a
Antibodies Single
Sony
HI149
Flow Cytometry,Immunohistochemistry
Mouse IgG1, κ
Human
2100505
$55.00
Add to Wish List

Description

CD1a is a 49 kD member of the immunoglobulin superfamily also known as T6 and R4. It is a type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. CD1a plays a role in non-peptide glycolipid antigen presentation to CD1-restricted T cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation, CD1a has been implicated in thymic T cell development.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 microg per million cells in 100 microL volume. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
2. Knapp W. 1989. Leucocyte Typing IV. Oxford University Press New York.
3. Patton KM, et al. 2005. Infect. Immun.73:2083. PubMed
4. Curti A, et al. 2010. Haematologica. 95:2022. PubMed