Purified anti-human CD94
Description
CD94 is a 43 kD type II transmembrane glycoprotein also known as KP43. CD94 belongs to the C-type lectin superfamily and is present as a covalently linked heterodimer with NKG2 on the cell surface. CD94 is expressed by NK cells, a subset of γδ T cells, and NKT cells. The CD94/NKG2A complex serves as an inhibitory receptor specific for HLA-class I molecules.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5 microg per million cells or 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
References
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2. Phillip J, et al. 1996. Immunity 5:163.
3. Lazetic S, et al. 1996. J. Immunol. 157:4741.
4. Lanier LL, et al. 1998. Immunity 8:693.
5. Wooden SL, et al. 2005. J. Immunol. 175:1383.
6. Shao DD, et al. 2008. J. Leukoc. Biol.83:1323. PubMed