FITC anti-mouse CD26 (DPP-4)

Antibodies Single
Sony
H194-112
Flow Cytometry
Rat IgG2a, κ
Mouse
BALB/c thymocytes
1289025
$70.00

Description

CD26, also known as DPP IV or THAM, is a 220 kD type II transmembrane homodimer. It consists of an α/β hydrolase domain and an eight-blade β-propeller domain.  After proteolysis of the membrane-bound CD26, a soluble form of DPP IV is released. CD26 is expressed on thymocytes (development dependent), T cells, B cells, NK cells, and macrophages. It is involved in T cell costimulation, endothelial cell migration and proteolysis processes.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 microg per million cells in 100 microL volume.  It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Naquet P, et al. 1988. J. Immunol. 141:4101.
2. Vivier I, et al. 1991. J. Immunol. 147:447.
2. Sen A, et al. 2012. PNAS PubMed.