APC anti-mouse CD279 (PD-1)

Antibodies Single
Sony
RMP1-30
Flow Cytometry
Rat IgG2b, κ
Mouse
Mouse PD-1 transfected BHK cells
1145555
$105.00

Description

CD279 is a 50-55 kD immunoglobulin superfamily member also known as programmed death-1 (PD-1). PD-1 is expressed on a subset of CD4-CD8- thymocytes and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 microg per million cells in 100 microL volume. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Matsumoto K, et al. 2004. J. Immunol. 172:2530.
2. Raimondi G, et al. 2006. J. Immunol. 176:2808. (FC) PubMed
3. King IL, et al. 2009. J. Exp Med 206:1001. (FC) PubMed