PE/Cy7 anti-human IFN-γ

Antibodies Single
Sony
4S.B3
Flow Cytometry
Mouse IgG1, κ
Human
Partially purified, native human IFN-γ
3112635
$139.00

Description

Interferon-γ is a potent multifunctional cytokine which is secreted primarily by activated NK cells and T cells. Originally characterized based on anti-viral activities, IFN-γ also exerts anti-proliferative, immunoregulatory, and proinflammatory activities. IFN-γ can upregulate MHC class I and II antigen expression by antigen-presenting cells.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 microL to 5 microL per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 microL staining volume or per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Meager A, et al. 1984. J. Interferon Res. 4:619. (Neut)
2. Meager A, 1987. Lymphokines and Interferons:A Practical Approach. IRL Press Ltd, Oxford, p. 105. (Neut)
3. Sester M, et al. 2002. J. Virol. 76:3748. (ICFC)
4. Infante-Duarte C, et al. 2000 J. Immunol. 165:6107. (ICFC)
5. Goodier M, et al. 2000. J. Immunol. 165:139. (ELISA)
6. Chen H, et al. 2005. J. Immunol. 175:591. (ICFC)
7. Smeltz RB, 2007. J. Immunol. 178:4786. (ICFC)
8. Iwamoto S, et al. 2007. J. Immunol. 179:1449. (ICFC) PubMed
9. Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (ICFC)
10. Brembilla NC, et al. 2011. PLoS One. 15:18741. PubMed
11. Jiang B, et al. 2014. Cell Immunol. 290:10. PubMed
12. Lim DS, et al. 2014. J Immunol. 193:5065. PubMed