-
Sign In
- Sony Biotechnology
- Sony Biotechnology
CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αx and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 microL per million cells or 5 microL per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
* PerCP/Cy5.5 has a maximum absorption of 482 nm and a maximun emission of 690 nm.
1. Sadhu C, et al. 2008. J. Immunoass. Immunoch. 29:42.
2. Rezzonico R, et al. 2001. Blood 97:2932.
3. Sadhu C, et al. 2007. J. Leukoc. Biol. 81:1395.
4. Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)