PerCP anti-human CD42b
Description
CD42b is a 145 kD glycoprotein known as gpIbα. It is covalently bonded to CD42c to form GPIb. CD42b is expressed on platelets and megakaryocytes. CD42b/c heterodimer forms a complex with CD42a and d and acts as the receptor for von Willibrand factor and thrombin.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 microg per million cells in 100 microL volume. It is recommended that the reagent be titrated for optimal performance for each application.
* PerCP has a maximum absorption of 482 nm and a maximum emission of 675 nm.
References
1. Knapp W, et al. 1989. Leucocyte Typing IV. Oxford University Press. New York.
2. Takahashi R, et al. 1999. Blood. 93:1951.
3. Saggu G, et al. 2013. J. Immunol. 190:6457. PubMed
4. Meyer Dos Santos S, et al. 2011. Blood. 117:4999. (Block) PubMed
5. Vettore S, et al. 2008. Haematologica. 93:1743.