Biotin anti-mouse CD21/CD35 (CR2/CR1)

Antibodies Single
Sony
7E9
Flow Cytometry
Rat IgG2a, κ
Mouse
CD35/CFA
1217030
$301.00

Description

CD21, also known as CR2 (complement receptor 2) and C3d receptor, binds C3d and iC3b. It is also a receptor of Epstein-Barr virus. CD35, also known as CR1, binds C3b, iC3b, C4b, and iC4b. CD21/CD35 is primarily expressed on B lymphocytes, mast cells, follicular dendritic cells, macrophages, and activated granulocytes. CD21/CD35 forms part of the B-cell antigen receptor complex with CD19 and CD81 and is involved in signal transduction.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 microg per 106 cells in 100 microL volume. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Boackle S, et al. 2001 Immunity 15:775.
2. Wang W, et al. 2014. J. Immunol. 192:3011. PubMed
3. Kajihara R, et al. 2014. J Immunol. 192:5720. PubMed