PE/Cy7 anti-mouse CD31

Antibodies Single
Sony
390
Flow Cytometry
Rat IgG2a, κ
Mouse
C3H/HeJ mouse hematopoietic progenitor cell line 3
1112085
$98.00

Description

CD31 is a 130-140 kD glycoprotein, also known as platelet endothelial cell adhesion molecule (PECAM-1) and EndoCAM. It is a member of the Ig superfamily, expressed on endothelial cells, platelets, granulocytes, monocytes/macrophages, dendritic cells, and T and B cell subsets, and is critical for cell-cell interactions. The primary ligands for CD31 have been reported to be CD38 and the vitronectin receptor (αv β3 integrin, CD51/CD61). Other reported functions of CD31 are neutrophil emigration to sites of inflammation and angiogenesis.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 microg per 106 cells in 100 microL volume. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Baldwin HS, et al. 1994. Development 120:2539. (IP, Block)
2. DeLisser HM, et al. 1997. Am. J. Pathol. 151:671. (Block)
3. Rosenblum WI, et al. 1996. Stroke 27:709. (Block)
4. Iguchi A, et al. 1997. Cell Struct. Funct. 22:357. (Block)
5. Wyder L, et al. 2000. Cancer Res. 60:4682. (IHC)
6. Wiewrodt R, et al. 2002. Blood 99:912. (IHC)
7. McQualter JL, et al. 2009. Stem Cells. 27:623. (IHC) PubMed
8. Chacko AM, et al. 2012. PLoS One 7:e34958. 
9. Ito K, et al. 2014. PNAS. 111:3080. PubMed