Description

CD10 is a 100 kD neutral endopeptidase and a member of the metalloprotease family. It is a type II transmembrane protein also known as common acute lymphoblastic leukemia antigen (CALLA), enkephalinase, and neprilysin. CD10 is expressed on B cell precursors, T cell precursors, and neutrophils. CD10 is involved in B cell development and has been shown to bind opioid enkephalins, bradykinin, angiotensins I and II, and other biologically active peptides.

Formulation

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

* APC/Fire™ 750 has a maximum excitation of 650 nm and a maximum emission of 787 nm.

References

1. Knapp W, et al. Eds. 1989. Leucocyte Typing IV. Oxford University Press. New York.
2. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
3. Edberg J, et al. 1997. J. Immunol. 159:3849. (IP)
4. Hoshino S, et al. 1991. Blood 78:3232. (Stim)
5. Tamm A, et al. 1996. Immunol. 157:1576. (Block)
6. Da Silva DM, et al. 2001. Int. Immunol. 13:633. (IHC)
7. Holl V, et al. 2004. J. Immunol. 173:6274. (Block)
8. Hober D, et al. 2002. J. Gen. Virol. 83:2169. (Block)
9. Brainard DM, et al. 2009. J. Virol. 83:7305. PubMed
10. Smed-Sörensen A, et al. 2008. Blood 111:5037. (Block) PubMed
11. Timmerman KL, et al. 2008. J. Leukoc. Biol. 84:1271. (FC) PubMed
12. Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
13. Rout N, et al. 2010. PLoS One 5:e9787. (FC)
14. Kim WK, et al. 2006. Am. J. Pathol. 168:822. (FC)
15. Boltz A, et al. 2011. J. Biol Chem. 286:21896. PubMed
16. Wu Z, et al. 2013. J. Virol. 87:7717. PubMed
17. Peterson VM, et al. 2017. Nat. Biotechnol. 35:936. (PG)
18. Vossebeld PJ, et al. 1997. Biochem J. 323:87-94 (Stim)