APC/Fire™ 750 anti-mouse CD198 (CCR8)

Antibodies Single
Sony
SA214G2
Flow Cytometry
Rat IgG2b, κ
Mouse
Mouse CD198 (CCR8)-transfected cells
1351585
$170.00

Description

C-C chemokine receptor type 8 (CCR8) CD198, is a 41 kD G-protein coupled receptor with 7 transmembrane regions. CCR8 is expressed by a subset of thymocytes, Tregs, NKT and Th2-polarized cells, a subset of macrophages, monocytes, and monocyte-derived dendritic cells. CCR8 mediates chemotaxis toward its ligand CCL1, and is involved in apoptosis of thymocytes.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

 

* APC/Fire™ 750 has a maximum excitation of 650 nm and a maximum emission of 787 nm.