Description

CD5, also known as Leu-1, Ly-1 and T1, is a 67 kD single chain type I glycoprotein that is a member of the scavenger receptor superfamily. CD5 is expressed on T cells, thymocytes, B cell subsets, chronic B lymphocytic leukemia (B-Cells), and peripheral blood dendritic cells. CD5 modulates T and B cell receptor signaling, thymocyte maturation, and T-B cell interactions. One of its ligands is CD72.

Formulation

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

* APC/Fire™ 750 has a maximum excitation of 650 nm and a maximum emission of 787 nm.

References

1. McAlister MS, et al. 1998. Protein Eng. 11:847. (IP)
2. Butmarc JR, et al. 1998. Am. J. Clin. Pathol. 109:682. (IHC)
3. Engleman EG, et al. 1981. Proc. Natl. Acad. Sci. USA 78:1791. (IHC, IP)
4. Ledbetter JA, et al. 1981. J. Exp. Med. 153:310. (FC, IP)
5. Warnke R and Levy R. 1980. J. Histochem. Cytochem. 28:771. (IHC)