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- Sony Biotechnology
- Sony Biotechnology
CD32B/C (FCGR2B/C) is a 40 kDa, type I transmembrane protein, member of the Ig superfamily; the cytoplasmic tail containis an immunoreceptor tyrosine-based inhibition motif (ITIM). CD32B/C is the low affinity receptor for monomeric IgG but also bind IgG complexes. CD32B/C is expressed on B cells, subsets of monocytes,macrophages and granulocytes, platelets, mast cells, and is a negative regulator of cell activation, proliferation, endocytosis, phagocytosis, and degranulation.
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.