PE anti-mouse CD20

Antibodies Single
Sony
SA271G2
Flow Cytometry
Rat IgG2b, κ
Mouse
Mouse CD20 transfected cells
1360530
$318.00

Description

CD20 is a 33-37 kD protein, a member of the MS4A family, with four transmembrane spanning regions that present as a homo-oligomeric complexes in the cell surface when associating with MHC class I and II, CD53, CD81, and CD82. CD20 is expressed on B cells and a subset of T cells, but not on plasma cells. CD20 regulates B-cell activation and proliferation. Its ligation promotes transmembrane Ca2+ trafficking. CD20 is an important therapeutic target in the treatment of B cell lymphomas and leukemias.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

References

  1. Hirsch MS, et al. 1997. Dev. Dyn. 210:249. (Block)
  2. Sawhney RS, et al. 2006. J. Biol. Chem. 281:8497. (Block)
  3. Lee SA, et al. 2009. Carcinogensis. 30:1872. (IP)
  4. Zßrate S, et al. 2004. J. Virol. 78:10839. (ELISA)