Alexa Fluor® 700 anti-human CD11c

Antibodies Single
Sony
3.9
Flow Cytometry
Mouse IgG1, κ
Human,Non-human primate,Other
2108240
$318.00

Description

CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αX and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

* Alexa Fluor® 700 has a maximum emission of 719 nm when it is excited at 633 nm / 635 nm. Prior to using Alexa Fluor® 700 conjugate for flow cytometric analysis, please verify your flow cytometer's capability of exciting and detecting the fluorochrome.

References

  1. Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
  2. Knapp W, et al. 1989. Leucocyte Typing IV Oxford University Press. New York.
  3. McMichael A, et al. Eds. 1987. Leucocyte Typing III Oxford University Press. New York.
  4. Vainer B, et al. 2000. Am. J. Surg. Pathol. 24:1115. (IHC)
  5. Ottonello L, et al. 1999. Blood 93:3505.
  6. Metelitsa LS, et al. 2002. Blood 99:4166.
  7. Sadhu C, et al. 2007. J. Leukoc. Biol. doi:10.1189/jlb.1106680. PubMed
  8. Ihanus E, et al. 2007. Blood 109:802-810.
  9. Gurer C, et al. 2008. Blood 112:1231. PubMed
  10. Asai A, et al. 2009. J. Lipid Res. 50:95. PubMed
  11. Yoshino N, et al. 2000. Exp. Anim. (Tokyo) 49:97. (FC)
  12. Sadhu C, et al. 2008. J. Immunoass. Immunoch. 29:42. (FC)