Alexa Fluor® 488 anti-mouse CD309 (VEGFR2, Flk-1)

Antibodies Single
Sony
Avas12
Flow Cytometry,Immunohistochemistry
Rat IgG2a, κ
Mouse
Murine Flk1 fused to hIgG Fc
1282035
$145.00

Description

CD309 is also known as vascular endothelial growth factor receptor 2 (VEGFR2) and fetal liver kinase-1 (Flk-1). CD309 is a member of the tyrosine protein kinase family that contains a single pass transmembrane receptor with a protein kinase domain and seven immunoglobulin-like domains in the extracellular region. CD309 is expressed at high levels in adult heart, lung, kidney, brain, and skeletal muscle. It's a receptor for VEGF or VEGFC, and plays an important role in the development of vascular endothelial cells, hematopoietic cells, and vascular permeability.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 microg per million cells in 100 microL volume. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor® 488 has a maximum emission of 519 nm when it is excited at 488 nm.

References

1. Kataoka H, et al. 1997. Dev. Growth Differ. 39:729. (WB)
2. Ishitobi H, et al. 2010. Exp. Anim. 59:615. (IHC)
3. Albiero M, et al. 2014. Diabetes. 63:1353. PubMed