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- Sony Biotechnology
CD29 is a 130 kD protein, also known as integrin β1, VLA-β chain, or GPIIa. It is a member of the integrin family, expressed broadly on leukocytes, endothelial cells, smooth muscle, and epithelial cells. In association with CD49a-f, CD29 forms the VLA-1 through VLA-6 complexes, respectively. It plays an important role in cell-cell or cell-matrix interaction. The HMß1-1 antibody reacts with both mouse and rat CD29. It is able to block cell adhesion and inhibit T cell proliferation.
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 microg per 106 cells in 100 microL volume. It is recommended that the reagent be titrated for optimal performance for each application.
1. Noto K, et al. 1995. Int. Immunol. 7:835.
2. Ridger VC, et al. 2001. J. Immunol. 166:3484.
3. Jia W, et al. 2005. Blood 106:3854.PubMed
4. Economopoulou M, et al. 2005. Blood 106:3831.
5. Lawson BR, et al. 2007. J. Immunol. 178:5366.
6. Eisenmann KM, et al. 2007. J. Biol. Chem. doi:10.1074/jbc.M703243200.PubMed
7. Hayashi Y, et al. 2008. Am J Physiol Gastrointest Liver Physiol. 294:G778. PubMed
8. Kim DT, et al. 2008. Blood 111:2929.PubMed
9. Hayashi Y, et al. 2008. J Pharmacol Exp Ther. 326:523. PubMed
10. Carlson TR, et al. 2008. Development. 135:2193. PubMed
11. Sangaletti S, et al. 2008. Cancer Res. 68:9050. (Block) PubMed
12. Takahashi M, et al. 2010. Am J Physiol Heart Circ Physiol. 298:415. PubMed
13. Watzlawik J, et al. 2010. Glia. 58:1782. PubMed
14. Rey-Barroso J, et al. 2013. Cell Signal. 25:848. PubMed
15. Cai WY, et al. 2013. J Cell Sci. 126:2877. PubMed
16. Contador-Troca M, et al. 2013. Carcinogenesis. 34:2683. PubMed
17. Zou MR, et al. 2014. J Biol Chem. 289:17620. PubMed