APC anti-human CD84

Antibodies Single
Sony
CD84.1.21
Flow Cytometry
Mouse IgG2a, κ
Human,Non-human primate,Other
300.19 cell line transfected with the CD84 full-length DNA
2230045
$157.00

Description

CD84 is a 64-82 kD glycoprotein. It is a member of the SLAM (CD150) family, a CD2 subset of the Ig superfamily, also known as SLAMF5 or Ly9b. CD84 is expressed on B cells, monocytes, thymocytes, subset of (preferentially on CD45RO+) T cells, and platelets. CD84 functions as a homophilic adhesion molecule and enhances T cell activation and cytokine production. The antibody CD84.1.21 is able to enhance CD3 induced IFN-γ production and partially block CD84-Ig binding to lymphocytes.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.

References

  1. Martin M, et al. 2001. J. Immunol. 167:3668.
  2. Sayos J, et al. 2001. Blood 97:3867.
  3. Morra M, et al. 2001. EMBO 20:5840.
  4. Morra M, 2001. J. Biol. Chem. 276:36809.
  5. Romero X, et al. 2004. Tissue Antigens 64:132.