Human rheumatoid synovial fluid cells and fibronectin-purified monocytes.
2125195
$121.00
Description
CD64 is a 72 kD single chain type I glycoprotein also known as FcγRI and FcR I. CD64 is a member of the immunoglobulin superfamily and is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. The expression can be upregulated by IFN-γ stimulation. CD64 binds IgG immune complex. It plays a role in antigen capture, phagocytosis of IgG/antigen complexes, and antibody-dependent cellular cytotoxicity (ADCC).
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells in 100 µl staining volume or 5 µl per 100 µl of whole blood.
References
McMichael A, et al. Eds. 1987. Leucocyte Typing III. Oxford University Press. New York.
Schlossman S, et al. Eds. 1995. Leucocyte Typing V. Oxford University Press. New York. p. 874.
Kishimoto T, et al. Eds. 1997. Leucocyte Typing VI. Garland Publishing Inc. London.
Holl V, et al. 2004. J. Immunol. 173:6274.
Hober D, et al. 2002. J. Gen. Virol. 83:2169.
Cho HJ, et al. 2007. Physiol Genomics 149:60.
van Tits L, et al. 2005. Arterioscler Thromb Vasc Biol. 25:717. PubMed