Purified anti-human CD110

Antibodies Single
Sony
S16017E
Flow Cytometry
Mouse IgG2a, κ
Human
Human CD110 transfectants
2568510
$187.00

Description

CD110 is a type I transmembrane glycoprotein which functions as a receptor for thrombopoietin; binding causes the proliferation and differentiation of megakaroyocytes in addition to the production of platelets and protection of stem cells from apoptosis. CD110 is primarily expressed on hematopoietic stem cells, hematopoietic precursor cells, cells of the megakaryocytic lineage, and platelets.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

References

  1. Ninos JM, et al. 2006. J. Transl. Med. 16:4-9.
  2. Broudy VC, et al. 1996. Blood. 88:2026-32.
  3. Wang X, et al. 2016. Blood. 127:3398-409.