PE/Cy7 anti-human CD82

Antibodies Single
Sony
ASL-24
Flow Cytometry
Mouse IgG1, κ
Human,Non-human primate
2310545
$117.00

Description

CD82 is a 45-90 kD type III tetraspan membrane protein which is encoded by the KAI1 gene. A member of the 4-span transmembrane protein superfamily (TM4SF) CD82 forms a complex with CD37, CD53, CD81, ECM and MHC molecules. CD82 is expressed on monocytes, granulocytes, lymphocytes, epithelial cells, endothelial cells, and fibroblasts and plays a role in signal transduction and adhesion. It has been suggested CD82 functions as a tumor suppressor as loss of expression has been found to promote tumor metastasis.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 µl per million cells or 5 µl per 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

References

1. Miranti CK. 2009. Cell. Signal. 21:196
2. Abe M, et al. 2008. 266:163
3. Lee JH et al. 2004. Cancer Res. 64:4235
4. Lagaudriere-Gesbert C, et al. 1997. J. Immunol. 158:2790