PerCP/Cy5.5 anti-human CD11c

Antibodies Single
Sony
S-HCL-3
Flow Cytometry
Mouse IgG2b, κ
Human
Spleen cells from patient diagnosed with hairy cell leukemia.
2457585
$174.00

Description

CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αx and CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells. CD11c has been reported to play a role in adhesion and CTL killing through its interactions with fibrinogen, CD54, and iC3b.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 microL per million cells or 5 microL per 100 microL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

* PerCP/Cy5.5 has a maximum absorption of 482 nm and a maximum emission of 690 nm.

References

1. Schwarting R, et al. 1985. Blood 65:974.
2. Knowles DM, et al. 1990. Am. J. Pathol. 136:29.
3. Vandenabeele S, et al. 2001. Blood 97:1733.
4. Shaw JL, et al. 2011. J. Reprod. Immunol. 89:84.