PE anti-mouse CD11c

Antibodies Single
Sony
N418
Flow Cytometry
Hamster IgG
Mouse
Mouse spleen dendritic cells
1186535
$73.00

Description

CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen, and CD54.

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 microg per 106 cells in 100 microL volume. It is recommended that the reagent be titrated for optimal performance for other applications.

References

1. Granucci F, et al. 1997. J. Immunol. 159:1794.
2. Stokes RW, et al. 1998. J. Immunol. 160:5514.
3. Metlay JP, et al. 1990. J. Exp. Med. 171:1753. (IHC, IP)
4. Ma XT, et al. 2006. Cancer Research 66:1169.
5. Chin RK, et al. 2006. J. Immunol. 177:290. (IF)
6. Cervantes-Barragan L, et al. 2007. Blood 109:1131. (FC) PubMed
7. Turnquist HR, et al. 2007. J. Immunol. 178:7018. (FC) PubMed
8. Benson MJ, et al. 2007. J. Exp. Med. doi:10.1084/jem.20070719. (FC) PubMed
9. You Y, et al. 2009. J. Immunol. 182:7343. (IF) PubMed
10. Roland CL, et al. 2009. Mol. Cancer Res. 8:1761. (IHC, FC) PubMed
11. Wikstrom M, et al.2006. J. Immunol. 177:913. PubMed
12. Pericolini E, et al. 2008. J. Leukocyte Biol. 83:1286. PubMed
13. Randall LM, et al. 2008. Infect. Immun.76:3312. PubMed
14. Fahlen-Yrild L, et al. 2009. J. Immunol. 183:5032. PubMed
15. Osterholzer JJ, et al. 2009. J. Immunol. 183:8044. PubMed
16. Bankoti J, et al. 2010. Toxicol. Sci. 115:422. (FC) PubMed
17. Eisenach PA, et al. 2010. J Cell Sci. 123:4182. PubMed
18. Leppin K, et al. 2014. Invest. Ophthalmol. Vis. Sci. 55:3603. PubMed
19. Al-Barwani F, et al. 2014. PLoS One. 9:104523. PubMed
20. Hanihara-Tatsuzaawa F, et al. 2014. J Biol Chem. 289:30925. PubMed
21. Olson MR, et al. 2014. J Immunol. 193:5420. PubMed
22. Iwai H, et al. 2015. Tuberculosis. 95:246. PubMed